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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » People & Locations » Alexandra Buckley
Alexandra Buckley
Virus and Prion Research
Research Veterinary Medical Officer

Phone: (515) 337-6309
Fax:

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Intervention Strategies to Control Endemic and New Emerging and Re-Emerging Viral Diseases of Swine
In-House Appropriated (D)
  Accession Number: 441144
Experimental Infections of Elk With SARS-CoV-2
Interagency Reimbursable Agreement (I)
  Accession Number: 442977
SARS-CoV-2 White-tailed Deer Infection Dynamics and Antibody Persistence
Interagency Reimbursable Agreement (I)
  Accession Number: 443025
Defining Antagonism Hierarchy of Porcine Epidemic Diarrhea Virus for Live Vaccines Design
Reimbursable Cooperative Agreement (R)
  Accession Number: 445534
Pathogenesis of Swine Acute Diarrhea Syndrome Coronavirus
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444456

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Evaluating control measures for Senecavirus A in the marketing chain - (Abstract Only)
Experimental Senecavirus A infection of bovine cell lines and colostrum-deprived calves - (Abstract Only)
Validation of a live-virus PRRSV vaccine candidate for efficient attenuation and better protection - (Abstract Only)
Genomic regions associated with pseudorabies virus infection status in naturally infected feral swine (Sus scrofa) Reprint Icon - (Peer Reviewed Journal)
Bowden, C.F., Kiser, J.N., Miller, R.S., Devries, A.C., Boggiatto, P.M., Giglio, R.M., Brown, V.R., Garrick, D., Neibergs, H.L., Piaggio, A.J., Speidel, S.E., Smyser, T.J. 2023. Genomic regions associated with pseudorabies virus infection status in naturally infected feral swine (Sus scrofa). Frontiers in Genetics. https://doi.org/10.3389/fgene.2023.1292671.
Dynamics of infection of atypical porcine pestivirus in commercial pigs from birth to market: A longitudinal study Reprint Icon - (Peer Reviewed Journal)
Devries, A.C., Mora-Diaz, J., Magtoto, R., Van Hulzen, A., Ferreyra, F., Falkenberg, S., Gimenez-Lirola, L., Arruda, B.L. 2023. Dynamics of infection of atypical porcine pestivirus in commercial pigs from birth to market: A longitudinal study. Viruses. 15(8):1767. https://doi.org/10.3390/v15081767.
Experimental challenge of a SARS-CoV-2 Omicron variant in American mink - (Abstract Only)
Longitudinal study of atypical porcine pestivirus infection dynamics in pigs from birth to market reveals persistent infection in piglets with congenital tremors - (Proceedings)
Devries, A.C., Mora-Diaz, J., Van Hulzen, A., Matias Ferreyra, F., Falkenberg, S., Gimenez-Lirola, L., Arruda, B.L. 2023. Longitudinal study of atypical porcine pestivirus infection dynamics in pigs from birth to market reveals persistent infection in piglets with congenital tremors. American Association of Swine Veterinarians Annual Meeting. AASV 2023 Proceedings, March 4-7, 2023, Aurora, Colorado.
Divergent pathology between highly pathogenic avian influenza A (H5N1) strains in swine - (Proceedings)
Arruda, B.L., Devries, A.C., Killian, M., Hines Bergeson, N., Torachetti, M., Baker, A.L. 2023. Divergent pathology between highly pathogenic avian influenza A (H5N1) strains in swine. American Association of Swine Veterinarians Annual Meeting. American Association of Swine Veterinarians Annual Meeting, March 4-7, 2023, Aurora, Colorado.
Experimental Senecavirus A infection of bovine cell lines and colostrum-deprived calves Reprint Icon - (Peer Reviewed Journal)
Devries, A.C., Crawford, L., Hoffman, K., Falkenberg, S. 2022. Experimental Senecavirus A infection of bovine cell lines and colostrum-deprived calves. Viruses. 14(12):Article 2809. https://doi.org/10.3390/v14122809.
Senecavirus A in the environment of sow slaughter plants Reprint Icon - (Proceedings)
Devries, A.C., Hoffman, K., Faaberg, K.S., Humphrey, N., Korslund, J., Lager, K.M. 2022. Senecavirus A in the environment of sow slaughter plants. American Association of Swine Veterinarians Annual Meeting. 22 June 2022. https://doi.org/10.3389/fvets.2022.923878.
SARS-CoV-2: Experimental studies on deer-to-deer transmission Reprint Icon - (Abstract Only)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G., Boggiatto, P.M., Kanipe, C.R., Fernandes, M. 2022. SARS-CoV-2: Experimental studies on deer-to-deer transmission. United States Animal Health Association Proceedings. [Abstract}. https://doi.org/10.1371/journal.ppat.1010197.
Experimental intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 Reprint Icon - (Proceedings)
Devries, A.C., Falkenberg, S.M., Martins, M., Palmer, M.V., Lager, K.M., Diel, D. 2022. Experimental intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2. Pig Veterinary Society International Congress Proceedings. Pg.6825 Abstract 473030. https://doi.org/10.3390/v13081506.
Evaluation of one versus two doses of an inactivated Senecavirus A vaccine in weaned pigs - (Proceedings)
Devries, A.C., Hoffman, K., Lager, K.M. 2022. Evaluation of one versus two doses of an inactivated Senecavirus A vaccine in weaned pigs. Pig Veterinary Society International Congress Proceedings. IPVS 2022 Proceedings.
Characterization of Senecavirus A isolates collected from the environment of U.S. sow slaughter plants Reprint Icon - (Peer Reviewed Journal)
Hoffman, K., Humphrey, N., Korslund, J., Anderson, T.K., Faaberg, K., Lager, K.M., Devries, A.C. 2022. Characterization of Senecavirus A isolates collected from the environment of U.S. sow slaughter plants. Frontiers in Veterinary Science. 9. Article 923878. https://doi.org/10.3389/fvets.2022.923878.
Infectious dose of Senecavirus A in market weight and neonatal pigs Reprint Icon - (Peer Reviewed Journal)
Devries, A.C., Lager, K.M. 2022. Infectious dose of Senecavirus A in market weight and neonatal pigs. PLoS ONE. 17(4). Article e0267145. https://doi.org/10.1371/journal.pone.0267145.
Rapid application of long-acting ceftiofur can prevent death losses associated with Streptococcus equi subspecies zooepidemicus in pigs Reprint Icon - (Peer Reviewed Journal)
Hau, S.J., Devries, A.C., Brockmeier, S. 2022. Rapid application of long-acting ceftiofur can prevent death losses associated with Streptococcus equi subspecies zooepidemicus in pigs. Swine Health and Production. 30(5):292-297. https://doi.org/10.54846/jshap/1298.
From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer Reprint Icon - (Peer Reviewed Journal)
Martins, M., Boggiatto, P.M., Buckley, A., Cassmann, E.D., Falkenberg, S.M., Caserta, L.C., Fernandes, M.H., Kanipe, C.R., Lager, K.M., Palmer, M.V., Diel, D.G. 2022. From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in highly susceptible white-tailed deer. PLoS Pathogens. 18(3). Article e1010197. https://doi.org/10.1371/journal.ppat.1010197.
Efficacy of an inactivated Senecavirus A vaccine in weaned pigs and mature sows Reprint Icon - (Peer Reviewed Journal)
Devries, A.C., Lager, K.M. 2022. Efficacy of an inactivated Senecavirus A vaccine in weaned pigs and mature sows. Vaccine. 40(12):1747-1754. https://doi.org/10.1016/j.vaccine.2022.02.018.
Bacterin vaccination provides insufficient protection against Streptococcus equi subspecies zooepidemicus infection in pigs Reprint Icon - (Peer Reviewed Journal)
Hau, S.J., Devries, A.C., Brockmeier, S. 2022. Bacterin vaccination provides insufficient protection against Streptococcus equi subspecies zooepidemicus infection in pigs. Frontiers in Veterinary Science. 9. Article 827082. https://doi.org/10.3389/fvets.2022.827082.
Prevention and control of Streptococcus equi subspecies zooepidemicus infection in pigs Reprint Icon - (Proceedings)
Hau, S.J., Devries, A.C., Brockmeier, S. 2022. Prevention and control of Streptococcus equi subspecies zooepidemicus infection in pigs. American Association of Swine Veterinarians Annual Meeting. Pg.51-52. https://doi.org/10.54846/am2022/14.
Senecavirus A in the environment of sow slaughter plants Reprint Icon - (Abstract Only)
Hoffman, K., Humphrey, N., Korslund, J., Faaberg, K.S., Lager, K.M., Devries, A.C. 2022. Senecavirus A in the environment of sow slaughter plants. Conference Research Workers Disease Meeting. 2022 Jun 22;9:923878. https://doi.org/10.3389/fvets.2022.923878.
Evaluation of one versus two doses of an inactivated Seneca Valley virus vaccine in weaned pigs Reprint Icon - (Abstract Only)
Hoffman, K., Lager, K.M., Devries, A.C. 2022. Evaluation of one versus two doses of an inactivated Seneca Valley virus vaccine in weaned pigs. American Association of Swine Veterinarians Annual Meeting. 2022 Mar 15;40(12):1747-1754. https://doi.org/10.54846/am2022/114.
Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 Reprint Icon - (Proceedings)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2021. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Biocontainment Network Monthly Scientific Seminar. 95(11):e00083-21 Meeting Abstract. https://doi.org/10.1128/JVI.00083-21.
Senecavirus A: Frequently asked questions Reprint Icon - (Peer Reviewed Journal)
Devries, A.C., Lager, K.M. 2022. Senecavirus A: Frequently asked questions. Swine Health and Production. 30(3):149-159. https://doi.org/10.54846/jshap/1270.
Intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 Reprint Icon - (Peer Reviewed Journal)
Buckley, A.C., Falkenberg, S.M., Martins, M., Laverack, M., Palmer, M.V., Lager, K.M., Diego, D. 2021. Intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2. Viruses. 13(8). https://doi.org/10.3390/v13081506.
Detection of pseudorabies virus antibody in swine serum oral fluid specimens using a recombinant gE glycoprotein dual matrix indirect ELISA Reprint Icon - (Peer Reviewed Journal)
Cheng, T., Magtoto, R., Henao-Diaz, A., Poonsuk, K., Devries, A.C., Van Geelen, A., Lager, K.M., Zimmerman, J., Gimenez-Lirola, L. 2021. Detection of pseudorabies virus antibody in swine serum oral fluid specimens using a recombinant gE glycoprotein dual matrix indirect ELISA. Journal of Veterinary Diagnostic Investigation. 33(6). p. 1106-1114. https://doi.org/10.1177/10406387211040755.
Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 - (Abstract Only)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2021. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Virtual. 86th North American Wildlife and Natural Resources Conference.
Experimental innoculation of young calves with SARS-CoV-2 Reprint Icon - (Peer Reviewed Journal)
Falkenberg, S.M., Buckley, A.C., Laverack, M., Martins, M., Palmer, M.V., Diel, D., Lager, K.M. 2021. Experimental innoculation of young calves with SARS-CoV-2. Viruses. 13(3). Article 441. https://doi.org/10.3390/v13030441.
Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 Reprint Icon - (Peer Reviewed Journal)
Palmer, M.V., Martins, M., Falkenberg, S.M., Buckley, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2021. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Journal of Virology. 95(11). Article e0008321. https://doi.org/10.1128/JVI.00083-21.
Pseudorabies (Aujeszky's disease) virus DNA detection in swine nasal swab and oral fluid specimens using a gB-based real-time quantitative PCR Reprint Icon - (Peer Reviewed Journal)
Cheng, T., Henao-Diaz, A., Poonsuk, K., Buckley, A.C., Van Geelen, A., Lager, K.M., Harmon, K., Gauger, P., Wang, C., Ambagala, A., Zimmerman, J., Gimenez-Lirola, L. 2021. Pseudorabies (Aujeszky's disease) virus DNA detection in swine nasal swab and oral fluid specimens using a gB-based real-time quantitative PCR. Preventive Veterinary Medicine. 189. Article 105308. https://doi.org/10.1016/j.prevetmed.2021.105308.
Distribution and persistence of atypical porcine pestivirus (APPV) in experimentally inoculated pigs Reprint Icon - (Peer Reviewed Journal)
Buckley, A.C., Falkenberg, S.M., Palmer, M.V., Arruda, P.H., Magstadt, D.R., Schwartz, K.J., Gatto, I., Neill, J.D., Arruda, B.L. 2021. Distribution and persistence of atypical porcine pestivirus (APPV) in experimentally inoculated pigs. Journal of Veterinary Diagnostic Investigation. 33(5):952-955. https://doi.org/10.1177/10406387211022683.
Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 - (Abstract Only)
Palmer, M.V., Martins, M., Falkenberg, S.M., Devries, A.C., Caserta, L.D., Mitchell, P.K., Wagner, B., Cassmann, E.D., Lager, K.M., Diel, D.G. 2020. Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2. Virtual Symposium. December 1-3, 2020.
Comparison of historical and contemporary isolates of Senecavirus A Reprint Icon - (Peer Reviewed Journal)
Buckley, A.C., Michael, D.D., Faaberg, K.S., Guo, B., Yoon, K., Lager, K.M. 2020. Comparison of historical and contemporary isolates of Senecavirus A. Veterinary Microbiology. 253. Article 108946. https://doi.org/10.1016/j.vetmic.2020.108946.
Pathogenesis and control of Senecavirus A in swine Reprint Icon - (Other)
Devries, A.C. 2021. Pathogenesis and control of Senecavirus A in swine. Iowa State University, Ames, Thesis. https://doi.org/10.31274/etd-20210114-20.
Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026 Reprint Icon - (Peer Reviewed Journal)
Deng, X., Buckley, A.C., Pillatzki, A., Lager, K.M., Baker, S.C., Faaberg, K.S. 2020. Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026. Virology. 553:35-45. https://doi.org/10.1016/j.virol.2020.11.002.
Inactivating multiple coronavirus interferon antagonists attenuates pathogenesis of porcine epidemic diarrhea virus - (Abstract Only)
Buckley, A.C., Deng, X., Pillatzki, A., Lager, K.M., Faaberg, K.S., Baker, S. 2021. Inactivating multiple coronavirus interferon antagonists attenuates pathogenesis of porcine epidemic diarrhea virus [abstract]. American Association of Swine Veterinarians Annual Meeting. Poster No. 37.
Experimental intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 - (Abstract Only)
Buckley, A.C., Falkenberg, S.M., Laverack, M., Martins, M., Palmer, M.V., Diel, D., Lager, K.M. 2020. Experimental intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 [abstract]. American Association of Swine Veterinarians Annual Meeting. p. 35-37.
Persistent infection and protection against Senecavirus A in pigs previously infected with a homologous and a heterologous isolate - (Abstract Only)
Preis, G., Devries, A.C., Wiese, W., Vannucci, F. 2021. Persistent infection and protection against Senecavirus A in pigs previously infected with a homologous and a heterologous isolate. American Association of Swine Veterinarians Annual Meeting. Poster No. 54.
Detection of pseudorabies virus in oral fluid specimen using real-time PCR - (Abstract Only)
Cheng, T., Harmon, K., Gauger, P., Wang, C., Ambagala, A., Buckley, A.C., Van Geelen, A., Lager, K.M., Zimmerman, J., Gimenez-Lirola, L. 2020. Detection of pseudorabies virus in oral fluid specimen using real-time PCR [abstract]. American Association of Veterinary Laboratory Diagnosticians. p. not available.
Inactivating three interferon antagonists attenuates pathogenesis of an enteric coronavirus Reprint Icon - (Peer Reviewed Journal)
Deng, X., Buckley, A.C., Pillatzki, A., Lager, K.M., Faaberg, K.S., Baker, S.C. 2020. Inactivating three interferon antagonists attenuates pathogenesis of an enteric coronavirus. Journal of Virology. 94(17). https://doi.org/10.1128/JVI.00565-20.
Detection of pseudorabies virus antibody in swine oral fluid using a serum whole-virus indirect ELISA Reprint Icon - (Peer Reviewed Journal)
Cheng, T., Buckley, A.C., Van Geelen, A., Lager, K.M., Henao-Diaz, A., Poonsuk, K., Pineyro, P., Ji, J., Wang, C., Main, R., Zimmerman, J., Gimenez-Lirola, L. 2020. Detection of pseudorabies virus antibody in swine oral fluid using a serum whole-virus indirect ELISA. Journal of Veterinary Diagnostic Investigation. https://doi.org/10.1177/1040638720924386.
The development of a diagnostic assay using oral fluids for the detection of Senecavirus A - (Abstract Only)
Zelenka, A.M., Buckley, A.C., Huang, Y.S., Hettenbach, S.M., Stack, J., Higgs, S., Vanlandingham, D.L. 2019. The development of a diagnostic assay using oral fluids for the detection of Senecavirus A [abstract]. Great Plains Infectious Disease meeting. Paper No. 1.
An overview of research at the National Animal Disease Center on endemic and emerging viral diseases of swine - (Abstract Only)
Anderson, T.K., Buckley, A.C., Miller, L.C., Fleming, D.S., Inderski, B., Lager, K.M., Faaberg, K.S. 2019. An overview of research at the National Animal Disease Center on endemic and emerging viral diseases of swine. Meeting Abstract. p. 80.
Porcine anti-viral immunity: how important is it? Reprint Icon - (Review Article)
Lager, K.M., Buckley, A.C. 2019. Porcine anti-viral immunity: how important is it? Frontiers in Immunology. 10:2258. https://doi.org/10.3389/fimmu.2019.02258.
Persistent atypical porcine pestivirus (APPV) infection in gilts - (Abstract Only)
Buckley, A.C., Arruda, B., Falkenberg, S.M., Miller, L.C., Lager, K.M. 2019. Persistent atypical porcine pestivirus (APPV) infection in gilts. Meeting Abstract. p. 35.
Efficacy of an inactivated Seneca Valley virus vaccine in pregnant sows - (Abstract Only)
Buckley, A.C., Lager, K.M. 2019. Efficacy of an inactivated Seneca Valley virus vaccine in pregnant sows. Meeting Abstract. p. 36.
Pseudorabies virus (PRV) antibody detection in swine serum and oral fluid specimens - (Abstract Only)
Cheng, T., Buckley, A.C., Van Geelen, A., Lager, K.M., Henao-Diaz, A., Poonsuk, K., Pineyro, P., Ji, J., Wang, C., Baum, D., Main, R., Zimmerman, J., Gimenez-Lirola, L. 2020. Pseudorabies virus (PRV) antibody detection in swine serum and oral fluid specimens. American Association of Swine Veterinarians Annual Meeting. Atlanta, Georgia. March 7-10, 2020, p. 37.
Characterization of homologous protective humoral immunity against Seneca Valley virus - (Abstract Only)
Kim, H., Buckley, A.C., Guo, B., Lager, K.M., Yoon, K. 2019. Characterization of homologous protective humoral immunity against Seneca Valley virus. Conference for Research Workers in Animal Diseases (CRWAD)2019 [abstract] p. 198.
Detection of pseudorabies virus (PRV) antibody in serum and oral fluid specimens from inoculated and/or vaccinated pigs using a whole virus indirect IgG ELISA - (Abstract Only)
Cheng, T., Buckley, A.C., Van Geelen, A., Lager, K.M., Henao-Diaz, A., Poonsuk, K., Pineyro, P., Wang, C., Baum, D., Main, R., Zimmerman, J., Gimenez-Lirola, L. 2019. Detection of pseudorabies virus (PRV) antibody in serum and oral fluid specimens from inoculated and/or vaccinated pigs using a whole virus indirect IgG ELISA. Meeting Abstract. Paper No. 45.
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