Multisensor Diagnostics (DBA Aidar Health) is a healthcare technology and digital medicine company with the mission to enhance the quality of life of patients with chronic conditions. The company has designed and developed a rapid vital health assessment device, MouthLab, that non-invasively measures 10+ vital health parameters including oral temperature, non-invasive blood pressure, respiratory rate, respiratory flow cycle morphology, pulse rate, ECG, oxygen saturation (SpO2), heart rate, heart rate variability, and basic lung functions in just 60 seconds. The data from the device is then sent via cellular network to a secure HIPAA-compliant cloud database, where the data is processed using proprietary algorithms. This data is then available and can be securely accessed by the users for overall health monitoring using a mobile application.

Broadly, the NSF SBIR Phase I project enabled the customization of the MouthLab (ML) device, and the patient mobile application (app), as well as building a novel physician surveillance system for remote detection and management of SARS-CoV-19 (COVID-19). This project advanced the development of the new device design for remote use through the design and execution of the Bluetooth module within the MouthLab device, allowing the reliable functioning of the solution, even in areas with low cellular network connectivity. The project funding also supported the conceptualization and implementation of a health status indicator on the patient mobile app, thereby enabling the general public who might not have the medical or scientific background to better understand the status of their daily health based on objective data collected using the MouthLab device. More importantly, the project helped develop an integrated COVID-19 surveillance/triage web dashboard for physicians through facilitating real-time transmission of key patient biometric data to ensure timely intervention, treatment modification, and prevention of potential complications at a very early stage.

The global COVID-19 pandemic has brought a sense of renewed urgency towards the development and deployment of high-quality, patient-centric, remote monitoring solutions. The societal benefits of this project are substantial. From a public health standpoint, remote monitoring can help avoid healthcare settings being inundated with patients, especially chronic patients who are susceptible to severe complications when they become infected with COVID-19. The MouthLab solution can also help prevent the spread of COVID-19 by allowing infected patients to be triaged and monitored at home rather than visiting an emergency room or clinic, thereby enabling better healthcare resource allocation and risk reduction. The MouthLab device and its supporting software can streamline the assessment and monitoring of symptom progression over days by creating a comprehensive snapshot of an individual?s health. Using the MouthLab remote monitoring solution, we aim to provide improved health outcomes for users through precision medicine, smarter engagement and tracking tools for care providers and caregivers, drug/treatment validation tools for biopharmaceuticals, and cost-effective solutions for payers. 

This project has laid the foundation for the MouthLab solution to emerge as a potent digital health tool that can enable multiple drug-development goals ? greater scientific understanding, more patient centric assessments and improved access to clinical trials which has been significantly disrupted by the pandemic. Ultimately, by leveraging the capabilities of MouthLab, we aim to create a new kind of personalized healthcare experience for users with a primary focus on virtual clinical trials and chronic disease management.

Last Modified: 01/26/2021
Modified by: Sathya Elumalai